For general purpose I would say the .45 if you don't reload or mind having to mail order ammo.
If you reload or like to stock up then the 10mm is a superior cartridge from a ballistics perspective. You can load it mild or wild which you can't really do with .45 acp.
But .45 is a lower pressure cartridge that is not as hard on the gun and ammo is much easier to find.
10mm is a magnum round that can be downloaded. .45 will never be a magnum round.
If you reload or like to stock up then the 10mm is a superior cartridge from a ballistics perspective. You can load it mild or wild which you can't really do with .45 acp.
But .45 is a lower pressure cartridge that is not as hard on the gun and ammo is much easier to find.
10mm is a magnum round that can be downloaded. .45 will never be a magnum round.
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