Zombie Deer

[bcj jones]

Has anyone heard of the "zombie deer" that has been reported in 24 States? "CWD or chronic wasting disease was reported in free-ranging deer, elk and/or moose has been reported in 24 states" "animals with the disease have a zombie-like stare and they become so gaunt that their rib cages become exposed" "they wander around aimless"

They are worried its contractible by eating an infected animal but aren't sure if humans can be affected by it. Weird stuff.

[AntlerCollector]

If you saw a deer like this would you eat it?

[antiparadigm]

Lol. No don't eat it. If you see it shoot and bring it to a TPWL check station. They will confirm CWD or not.

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[antiparadigm]

Try to eliminate the animals and contain the disease.

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[bossbowman]

http://discussions.texasbowhunter.co...d.php?t=680860 ...the joe rogan podcast is a good one too listen to

[bcj jones]

If you saw a deer like this would you eat it?

I definitely wouldn't it eat. What I was trying to point out is if a deer was in the early stages of the infection, but not showing any signs yet, and someone was to eat it.

I just heard about this, Ill have to listen to Joe Rogans pod cast

[Capt.Brown]

Lol. No don't eat it. If you see it shoot and bring it to a TPWL check station. They will confirm CWD or not.

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It takes weeks before the results come back, I’ve done it.

[-HIC-]

This has been a concern for a long time but it seems strange that TP&W has not done a great job of getting the word out. I asked a few folks at the lease and most had no idea what I was talking about.

I guess it is always top of mind for me because we have a thread discussing it frequently.

[Landrover]

Been on TBH for a decade as many are concerned about western hunting . Texas has been monitoring for years also. Yes, spreading into Texas. Preliminary findings that it is not transferred to humans but I'm not interested in trying it for dinner. The disease comes and goes based on conditions. I'm sure this is another spike.

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[WamBow]

Not a conspiracy theorist but I can see anti hunting groups using this "concern" to stop hunting. Claims like "it can take years for CWD to affect humans and that the symptoms of CWD in deer aren't immediate so hunters may not recognize a deer that's infected... it's a human health issue that's just not worth the risk!". Use alert language with ambiguous science as support. I don't like it.

https://www.foxnews.com/health/deadly-zombie-deer-disease-could-possibly-spread-to-humans-experts-warn

[Deerguy]

The disease comes and goes based on conditions. I'm sure this is another spike.

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Not sure on this one? There really is no cyclical nature to CWD. Once in an area, it persists for a long time, increasing in prevalence (slow increase in low density situations, fast increase in high density situations). Don't even really know how long as no known CWD area that I've heard of has decreased in prevalence (other than in depopulation cases and areas where culling has slowed the spread of the disease).

[Texans42]

Not a conspiracy theorist but I can see anti hunting groups using this "concern" to stop hunting. Claims like "it can take years for CWD to affect humans and that the symptoms of CWD in deer aren't immediate so hunters may not recognize a deer that's infected... it's a human health issue that's just not worth the risk!". Use alert language with ambiguous science as support. I don't like it.

https://www.foxnews.com/health/deadl...s-experts-warn

Have you not read any of flounder1’s posts. He probably wrote the article for Fox, Not an animal or fish that doesn’t have the ability to carry the diseased prion according to him. Good luck, go vegan or go home. Well except you are more 1000x more likely to die from ecoli on spinach then CWD in deer

[WamBow]

Have you not read any of flounder1’s posts. He probably wrote the article for Fox, Not an animal or fish that doesn’t have the ability to carry the diseased prion according to him. Good luck, go vegan or go home. Well except you are more 1000x more likely to die from ecoli on spinach then CWD in deer

Agreed!

Did I misinterpret your response or you mine?

[Texans42]

Agreed!

Did I misinterpret your response or you mine?

It was in support of yours, just not well articulated.

[flounder9]

'zombie' deer. oh please!

the sad part is, with this type of description, it's terribly misleading, because a perfectly healthy looking subclinical cwd tse prion deer is just as dangerous as one that is clinical.

Experts: Yes, chronic wasting disease in deer is a public health issue — for people

snip...

Michael Osterholm, director for the University of Minnesota's Center for Infectious Disease Research and Policy who sat on a panel of experts tracking the emergence of mad cow disease, or BSE, decades ago, told lawmakers this:

"It is my best professional judgment based on my public health experience and the risk of BSE transmission to humans in the 1980s and 1990s and my extensive review and evaluation of laboratory research studies ... that it is probable that human cases of CWD associated with the consumption of contaminated meat will be documented in the years ahead. It is possible that number of human cases will be substantial and will not be isolated events."

https://www.winonadailynews.com/news/local/experts-yes-chronic-wasting-disease-in-deer-is-a-public/article_fa49cff4-336f-5e18-9a66-c2248e8df354.html

Chronic Wasting Disease CWD TSE Prion aka mad deer disease zoonosis


We hypothesize that:

(1) The classic CWD prion strain can infect humans at low levels in the brain and peripheral lymphoid tissues;

(2) The cervid-to-human transmission barrier is dependent on the cervid prion strain and influenced by the host (human) prion protein (PrP) primary sequence;

(3) Reliable essays can be established to detect CWD infection in humans; and

(4) CWD transmission to humans has already occurred. We will test these hypotheses in 4 Aims using transgenic (Tg) mouse models and complementary in vitro approaches.

http://grantome.com/grant/NIH/R01-NS088604-04

ZOONOTIC CHRONIC WASTING DISEASE CWD TSE PRION UPDATE

here is the latest;

PRION 2018 CONFERENCE

Oral transmission of CWD into Cynomolgus macaques: signs of atypical disease, prion conversion and infectivity in macaques and bio-assayed transgenic mice

Hermann M. Schatzl, Samia Hannaoui, Yo-Ching Cheng, Sabine Gilch (Calgary Prion Research Unit, University of Calgary, Calgary, Canada) Michael Beekes (RKI Berlin), Walter Schulz-Schaeffer (University of Homburg/Saar, Germany), Christiane Stahl-Hennig (German Primate Center) & Stefanie Czub (CFIA Lethbridge).

To date, BSE is the only example of interspecies transmission of an animal prion disease into humans. The potential zoonotic transmission of CWD is an alarming issue and was addressed by many groups using a variety of in vitro and in vivo experimental systems. Evidence from these studies indicated a substantial, if not absolute, species barrier, aligning with the absence of epidemiological evidence suggesting transmission into humans. Studies in non-human primates were not conclusive so far, with oral transmission into new-world monkeys and no transmission into old-world monkeys. Our consortium has challenged 18 Cynomolgus macaques with characterized CWD material, focusing on oral transmission with muscle tissue. Some macaques have orally received a total of 5 kg of muscle material over a period of 2 years.

After 5-7 years of incubation time some animals showed clinical symptoms indicative of prion disease, and prion neuropathology and PrPSc deposition were detected in spinal cord and brain of some euthanized animals. PrPSc in immunoblot was weakly detected in some spinal cord materials and various tissues tested positive in RT-QuIC, including lymph node and spleen homogenates. To prove prion infectivity in the macaque tissues, we have intracerebrally inoculated 2 lines of transgenic mice, expressing either elk or human PrP. At least 3 TgElk mice, receiving tissues from 2 different macaques, showed clinical signs of a progressive prion disease and brains were positive in immunoblot and RT-QuIC. Tissues (brain, spinal cord and spleen) from these and pre-clinical mice are currently tested using various read-outs and by second passage in mice. Transgenic mice expressing human PrP were so far negative for clear clinical prion disease (some mice >300 days p.i.). In parallel, the same macaque materials are inoculated into bank voles.

Taken together, there is strong evidence of transmissibility of CWD orally into macaques and from macaque tissues into transgenic mouse models, although with an incomplete attack rate.

The clinical and pathological presentation in macaques was mostly atypical, with a strong emphasis on spinal cord pathology.
Our ongoing studies will show whether the transmission of CWD into macaques and passage in transgenic mice represents a form of non-adaptive prion amplification, and whether macaque-adapted prions have the potential to infect mice expressing human PrP.

The notion that CWD can be transmitted orally into both new-world and old-world non-human primates asks for a careful reevaluation of the zoonotic risk of CWD..

***> The notion that CWD can be transmitted orally into both new-world and old-world non-human primates asks for a careful reevaluation of the zoonotic risk of CWD. <***

https://prion2018.org/

READING OVER THE PRION 2018 ABSTRACT BOOK, LOOKS LIKE THEY FOUND THAT from this study ;

P190 Human prion disease mortality rates by occurrence of chronic wasting disease in freeranging cervids, United States

Abrams JY (1), Maddox RA (1), Schonberger LB (1), Person MK (1), Appleby BS (2), Belay ED (1) (1) Centers for Disease Control and Prevention (CDC), National Center for Emerging and Zoonotic Infectious Diseases, Atlanta, GA, USA (2) Case Western Reserve University, National Prion Disease Pathology Surveillance Center (NPDPSC), Cleveland, OH, USA..

SEEMS THAT THEY FOUND Highly endemic states had a higher rate of prion disease mortality compared to non-CWD
states.

AND ANOTHER STUDY;

P172 Peripheral Neuropathy in Patients with Prion Disease

Wang H(1), Cohen M(1), Appleby BS(1,2) (1) University Hospitals Cleveland Medical Center, Cleveland, Ohio (2) National Prion Disease Pathology Surveillance Center, Cleveland, Ohio..

IN THIS STUDY, THERE WERE autopsy-proven prion cases from the National Prion Disease Pathology Surveillance Center that were diagnosed between September 2016 to March 2017,

AND

included 104 patients. SEEMS THEY FOUND THAT The most common sCJD subtype was MV1-2 (30%), followed by MM1-2 (20%),

AND

THAT The Majority of cases were male (60%), AND half of them had exposure to wild game.

snip...

see more on Prion 2017 Macaque study from Prion 2017 Conference and other updated science on cwd tse prion zoonosis below...terry

https://prion2018.org/wp-content/uploads/2018/05/program.pdf

https://prion2018.org/

THURSDAY, OCTOBER 04, 2018

Cervid to human prion transmission 5R01NS088604-04 Update

http://grantome.com/grant/NIH/R01-NS088604-04

http://chronic-wasting-disease.blogspot.com/2018/10/cervid-to-human-prion-transmission.html

THURSDAY, FEBRUARY 14, 2019

Norway Eradication of Chronic Wasting Disease is not completed

https://chronic-wasting-disease.blogspot.com/2019/02/norway-eradication-of-chronic-wasting.html

terry