Improving mpg in F250 7.3

[Canoe1]

I finally got a truck I've wanted for a good while. Now I'm wanting to customize it some.
What are some of the tricks to improving mpg (and power) in a F250 with 7.3 in it?
What helps, what doesn't?
Right now it's all stock.

[oktx]

Inflate tires and slow down.

[LarryP_1989]

Cold air intake and straight pipe

[Canoe1]

Keeping the rpm under 2k (65mph). Easy on takeoffs. Tire presure good.

What kind of intake? Seen alot talk about the 6637 (I think that's the one).
I don't like straight pipes, but am thinking of 4 or 5". Would that help?

[Okiehunter]

CNG Assist will get you in the mid 40's or so I am told.

Diesel pickup owners have a natural gas option right now. You can convert your turbodiesel Ford, Chevy, or Dodge to run on a mixture of between 50% and 75% natural gas. Your diesel mileage should be 40 mpg or better.

[BigYoung]

Inflate tires and slow down.

x2