I would recommend Super Seal over Slime. They use Super Seal in tractor tires. It has slivers of rubber and anti freeze to better adhesion to the tire where the puncture occurred. A pint per tire. Get you some Essex Sure Foots. They are awesome tires, kevlar lined with run flat technology.
I don't use slime, I use some stuff called berrymans. It comes in a gallon jug with a pump top. I put a quart in each tire, haven't had any problems. At first that much in there will throw off the balance but after a while it goes away.
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