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    Originally posted by justletmein View Post
    You mean how they're coincidentally geographically located all around the breeding facilities?
    See the post below yours. CWD didn’t just show up in a breeder pen. Nor did those deer just appear in a pen. God created it. It is naturally occurring. I just want the breeder haters to use common sense instead of reacting based on emotion and self interest(not aimed at any one person)

    And breeder operations are tested at a far high percentage compared to free range. Kinda like Covid. Run more tests. Find more positives.

    Comment


      Originally posted by trophy8 View Post
      [ATTACH]1087077[/ATTACH]

      This map from the link Flounder posted is interested. Especially the amount of places it’s found free range.
      Something I find interesting is there are 2 epicenters in that map. One in the US and one in Canada. Are breeders sending deer from Colorado to Saskatchewan and vice versa on a regular basis?

      Logically there is only two explanations that would make sense; CWD has been around forever and we have only recently been able to test for it and find it or it started in a pen in one of those places and the transfer of one to the other caused it.

      Comment


        Originally posted by diamond10x View Post
        Something I find interesting is there are 2 epicenters in that map. One in the US and one in Canada. Are breeders sending deer from Colorado to Saskatchewan and vice versa on a regular basis?

        Logically there is only two explanations that would make sense; CWD has been around forever and we have only recently been able to test for it and find it or it started in a pen in one of those places and the transfer of one to the other caused it.
        I’d lean towards herd migrations spreading it. But I ain’t no scientist!

        Comment


          The new Kimble county ones are concerning to me and makes me wonder what they did with that facility. They are from facility number 6 which is where it was originally detected in Kimble county February of 2020. My understanding was the facility was depopulated. So, they either repopulated or never depopulated. If they did depopulate, why would you repopulate it so soon? TPWD continues to baffle me with their decisions.

          Comment


            Originally posted by Ag 89 View Post
            The new Kimble county ones are concerning to me and makes me wonder what they did with that facility. They are from facility number 6 which is where it was originally detected in Kimble county February of 2020. My understanding was the facility was depopulated. So, they either repopulated or never depopulated. If they did depopulate, why would you repopulate it so soon? TPWD continues to baffle me with their decisions.
            Or it’s still in the ground. Curious on how long it stays alive

            Comment


              Originally posted by trophy8 View Post
              Or it’s still in the ground. Curious on how long it stays alive
              I’ve heard and read from 2 years to thousands of years... huge difference there. I’m not a scientist either haha

              Comment


                Originally posted by trophy8 View Post
                Or it’s still in the ground. Curious on how long it stays alive
                They are pretty sure it stays in the ground for a prolonged period (time they really don't know). That's why I am baffled that they would repopulate that ranch so soon. I would think a minimum of 5 years before repopulating would be more sensible. Maybe I answered my own question, sensible and TPWD often are mutually exclusive.

                Comment


                  Originally posted by Ag 89 View Post
                  The new Kimble county ones are concerning to me and makes me wonder what they did with that facility. They are from facility number 6 which is where it was originally detected in Kimble county February of 2020. My understanding was the facility was depopulated. So, they either repopulated or never depopulated. If they did depopulate, why would you repopulate it so soon? TPWD continues to baffle me with their decisions.
                  Voluntary Chronic Wasting Disease Herd Certification Program Annual Update, FY2020

                  Last Modified: Feb 9, 2021

                  U.S. Department of Agriculture

                  Animal and Plant Health Inspection Service (APHIS) Veterinary Services

                  Annual Update from the Cervid Health Team

                  Voluntary Chronic Wasting Disease Herd Certification Program (HCP)

                  The APHIS National CWD Herd Certification Program (HCP) was implemented in 2014. It is a voluntary Federal-State-industry cooperative program administered by APHIS and implemented by participating States. The program provides uniform national herd certification standards that minimize the risk of spreading CWD in farmed cervid populations. Participating States and herd owners must comply with requirements for animal identification, fencing, recordkeeping, inspections/inventories, as well as animal mortality testing and response to any CWD-exposed, suspect, and positive herds. APHIS monitors the Approved State HCPs to ensure consistency with Federal standards through annual reporting by the States.

                  With each year of successful surveillance, herds participating in the HCP will advance in status until reaching five years with no evidence of CWD, at which time herds are certified as being low risk for CWD. Only farmed cervids from enrolled herds certified as low risk for CWD may move interstate. FY 2020 marks the eighth year that Approved States have submitted their CWD HCP annual reports to APHIS.

                  The current Cervid Health Program staff officers are as follows: Dr. Mark Lyons, Dr. Jennifer Siembieda, and Dr. Tracy Nichols

                  Voluntary Herd Certification Participation Summary

                  Currently, 28 States participate in the voluntary CWD Herd Certification Program encompassing 2,145 enrolled herds, of which, 1,723 had the certified status in the program.

                  1,616 enrolled deer herds, of which, 1,297 were certified

                  371 enrolled elk herds, of which, 328 were certified

                  147 enrolled mixed species herds, of which, 98 were certified

                  CWD in Farmed Cervids Summary of CW Detections

                  There were 22 newly identified CWD positive herds in FY20

                  13 of these herds were not participants in the Federal HCP

                  2 herds were considered enrolled in the HCP

                  7 herds were certified in the HCP

                  Half of the herds were located within 20 miles of identified CWD in the wild, half were not CWD Herds by State

                  Pennsylvania: Eight new CWD positive herds

                  Breeding herd of 33 WTD, HCP certified, depopulated with Federal indemnity

                  Breeding herd of 6 WTD, not in HCP, depopulated with Federal indemnity

                  Breeding herd of 15 WTD, not in HCP, depopulated by owner\

                  Hunt preserve of 58 WTD, not in HCP, populated and under quarantine

                  Breeding herd of 75 WTD, not in HCP, populated and under quarantine

                  Breeding herd of WTD, not in HCP, populated and under quarantine

                  Breeding herd of 90 WTD, not in HCP, populated and under quarantine

                  Breeding herd of 4 WTD, not in HCP, populated and under quarantine

                  Iowa: Two new CWD positive herds

                  Breeding herd of 23 WTD, HCP certified, depopulated with Federal indemnity

                  Breeding herd of 13 WTD, HCP certified, depopulated with Federal indemnity

                  Minnesota: Two new CWD positive herds

                  Breeding herd of 3 WTD, enrolled in HCP, not certified, depopulated by owner

                  Breeding herd of 6 WTD, enrolled in HCP, not certified, depopulated with Federal indemnity

                  Colorado: Two new CWD positive herds

                  Breeding herd/hunt preserve of 9 elk, HCP certified, depopulated by owner

                  Breeding herd of 8 elk, HCP certified, populated and under quarantine

                  Utah: Two new CWD positive herds

                  Breeding herd of 465 elk, not in HCP, partial depopulation with Federal indemnity- removed purchased animals, populated-quarantine

                  Breeding herd of 103 elk, not in HCP, partial depopulation with Federal indemnity- removed purchased animals, populated-quarantine

                  Michigan: One new CWD positive herd

                  Hunt preserve of >600 WTD, not in HCP, populated and under quarantine

                  Montana: One new CWD positive herd

                  Breeding herd of 3 elk, not in HCP, populated and under quarantine

                  Texas: one new CWD positive herd

                  Breeding herd of 59 WTD, not in HCP, depopulated with Federal indemnity

                  Kansas: One new CWD positive herd

                  Breeding herd of 20 elk, HCP certified, depopulated with Federal indemnity

                  Ohio: Eight new CWD positive herd

                  Breeding herd of 138 WTD, HCP certified, depopulated with Federal indemnity

                  Research

                  Whole genome study investigating the association of genetics with CWD susceptibility has been published.

                  Blinded validation of the genetic predicative model is almost complete

                  A standardized protocol has been developed, in partnership with ARS, USGS, University of WI, and NIH for tissue sample testing using RT-QuIC

                  A study is starting shortly to determine the sensitivity and specify of RT-QuIC utilizing the standardized protocol

                  snip...

                  Voluntary Chronic Wasting Disease Herd Certification Program Annual Update, FY2020



                  Cervids: CWD Voluntary Herd Certification Program

                  Last Modified: Jun 29, 2021

                  The CWD Herd Certification Program is a cooperative effort between the Animal and Plant Health Inspection Service, State animal health and wildlife agencies, and farmed cervid owners.


                  CWD status of captive herds



                  SUNDAY, OCTOBER 24, 2021

                  Voluntary Chronic Wasting Disease Herd Certification Program Annual Update, FY2020



                  CWD Quarantines equal CWD time bomb waiting to go off...terry

                  ***> Texas Chronic Wasting Disease CWD TSE Prion Confirmed Positive Jumps By 91 Total To Date 361 Cases

                  TEXAS CWD TRACKING

                  CWD Positive

                  Confirmation Date Free Range/Captive County Source Species Sex Age

                  Pending Breeder Deer Kimble Facility #6 White-tailed Deer Unknown 3.5
                  Pending Breeder Deer Hunt Facility #9 White-tailed Deer M 1.9
                  N/A Free Range Hartley N/A Mule Deer M 5.5
                  2022-01-25 Free Range Medina N/A White-tailed Deer F 5.5
                  2022-01-12 Breeder Deer Hunt Facility #9 White-tailed Deer M 1.5
                  2022-01-12 Breeder Deer Hunt Facility #9 White-tailed Deer F 3.5
                  2022-01-12 Breeder Release Site Medina Facility #3 Red Deer F 4.5
                  2022-01-12 Free Range Hartley N/A White-tailed Deer M 3.5
                  2022-01-12 Free Range Hartley N/A Mule Deer M 5.5
                  2022-01-12 Free Range Hartley N/A Mule Deer M 4.5
                  2022-01-12 Free Range Hartley N/A Mule Deer M 5.5
                  2022-01-12 Free Range Hartley N/A Mule Deer F 3.5
                  2022-01-12 Breeder Deer Kimble Facility #6 White-tailed Deer Unknown 5.5
                  2022-01-12 Free Range Hartley N/A Mule Deer M 3.5
                  2022-01-12 Free Range Hartley N/A Mule Deer M 7.5
                  2022-01-10 Free Range Medina N/A White-tailed Deer M 4.5
                  2022-01-10 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.3
                  2022-01-10 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 5.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 3.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 3.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 3.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 3.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 3.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer F 1.4
                  2022-01-07 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 5.4
                  2022-01-06 Free Range Medina N/A White-tailed Deer M 2.5
                  2021-12-28 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 3.4
                  2021-12-28 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 3.4
                  2021-12-13 Free Range Medina N/A White-tailed Deer M 3.5
                  2021-12-13 Breeder Deer Duval Facility #13 White-tailed Deer F 4.4
                  2021-12-13 Free Range El Paso N/A Mule Deer F 4.5
                  2021-10-18 Breeder Deer Medina Facility #4 White-tailed Deer M 4
                  2021-10-12 Breeder Deer Hunt Facility #9 White-tailed Deer F 8.2
                  2021-10-12 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.2
                  2021-10-12 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.2
                  2021-10-12 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 1.2
                  2021-10-12 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.2
                  2021-10-12 Breeder Deer Uvalde Facilities #7 & 8 White-tailed Deer M 2.1

                  Showing 1 to 100 of 361 entries Previous Next

                  National CWD Tracking Map



                  “Regarding the current situation involving CWD in permitted deer breeding facilities, TPWD records indicate that within the last five years, the seven CWD-positive facilities transferred a total of 2,530 deer to 270 locations in 102 counties and eight locations in Mexico (the destinations included 139 deer breeding facilities, 118 release sites, five Deer Management Permit sites, and three nursing facilities).'' ...

                  It is apparent that prior to the recent emergency rules, the CWD detection rules were ineffective at detecting CWD earlier in the deer breeding facilities where it was eventually discovered and had been present for some time; this creates additional concern regarding adequate mitigation of the risk of transferring CWD-positive breeder deer to release sites where released breeder deer come into contact with free-ranging deer...

                  Commission Agenda Item No. 5 Exhibit B

                  DISEASE DETECTION AND RESPONSE RULES
                  PROPOSAL PREAMBLE

                  1. Introduction.

                  snip...

                  A third issue is the accuracy of mortality reporting. Department records indicate that for each of the last five years an average of 26 deer breeders have reported a shared total of 159 escapes. Department records for the same time period indicate an average of 31 breeding facilities reported a shared total of 825 missing deer (deer that department records indicate should be present in the facility, but cannot be located or verified).



                  Listen here;

                  Nov 3, 2021



                  Nov 4, 2021



                  Counties where CWD Exposed Deer were Released, September 2021



                  Number of CWD Exposed Deer Released by County, September 2021



                  SATURDAY, FEBRUARY 26, 2022

                  Texas Chronic Wasting Disease CWD TSE Prion Confirmed Positive Jumps By 91 Total To Date 361 Cases

                  Comment


                    Originally posted by diamond10x View Post
                    I’ve heard and read from 2 years to thousands of years... huge difference there. I’m not a scientist either haha
                    TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY TSE PRION MAD COW TYPE DISEASE

                    THE tse prion aka mad cow type disease is not your normal pathogen.

                    The TSE prion disease survives ashing to 600 degrees celsius, that’s around 1112 degrees farenheit.

                    you cannot cook the TSE prion disease out of meat.

                    you can take the ash and mix it with saline and inject that ash into a mouse, and the mouse will go down with TSE.

                    Prion Infected Meat-and-Bone Meal Is Still Infectious after Biodiesel Production as well.

                    the TSE prion agent also survives Simulated Wastewater Treatment Processes.

                    IN fact, you should also know that the TSE Prion agent will survive in the environment for years, if not decades.

                    you can bury it and it will not go away.

                    The TSE agent is capable of infected your water table i.e. Detection of protease-resistant cervid prion protein in water from a CWD-endemic area.

                    it’s not your ordinary pathogen you can just cook it out and be done with.

                    ***> that’s what’s so worrisome about Iatrogenic mode of transmission, a simple autoclave will not kill this TSE prion agent.

                    1: J Neurol Neurosurg Psychiatry 1994 Jun;57(6):757-8

                    ***> Transmission of Creutzfeldt-Jakob disease to a chimpanzee by electrodes contaminated during neurosurgery.

                    Gibbs CJ Jr, Asher DM, Kobrine A, Amyx HL, Sulima MP, Gajdusek DC.

                    Laboratory of Central Nervous System Studies, National Institute of

                    Neurological Disorders and Stroke, National Institutes of Health,

                    Bethesda, MD 20892.

                    Stereotactic multicontact electrodes used to probe the cerebral cortex of a middle aged woman with progressive dementia were previously implicated in the accidental transmission of Creutzfeldt-Jakob disease (CJD) to two younger patients. The diagnoses of CJD have been confirmed for all three cases. More than two years after their last use in humans, after three cleanings and repeated sterilisation in ethanol and formaldehyde vapour, the electrodes were implanted in the cortex of a chimpanzee. Eighteen months later the animal became ill with CJD. This finding serves to re-emphasise the potential danger posed by reuse of instruments contaminated with the agents of spongiform encephalopathies, even after scrupulous attempts to clean them.

                    PMID: 8006664 [PubMed - indexed for MEDLINE]

                    Stereotactic multicontact electrodes used to probe the cerebral cortex of a middle aged woman with progressive dementia were previously implicated in the accidental transmission of Creutzfeldt-Jakob disease (CJD) to two younger patients. The diagnoses of CJD have been confirmed for all three cases. …


                    New studies on the heat resistance of hamster-adapted scrapie agent: Threshold survival after ashing at 600°C suggests an inorganic template of replication



                    Prion Infected Meat-and-Bone Meal Is Still Infectious after Biodiesel Production



                    MONDAY, APRIL 19, 2021

                    Evaluation of the application for new alternative biodiesel production process for rendered fat including Category 1 animal by-products (BDI-RepCat® process, AT) ???



                    Detection of protease-resistant cervid prion protein in water from a CWD-endemic area

                    https://www.ncbi...nlm.nih.gov/pmc/a...n0303_0171.pdf

                    A Quantitative Assessment of the Amount of Prion Diverted to Category 1 Materials and Wastewater During Processing



                    Rapid assessment of bovine spongiform encephalopathy prion inactivation by heat treatment in yellow grease produced in the industrial manufacturing process of meat and bone meals



                    THURSDAY, FEBRUARY 28, 2019

                    BSE infectivity survives burial for five years with only limited spread



                    5 or 6 years quarantine is NOT LONG ENOUGH FOR CWD TSE PRION !!!

                    QUARANTINE NEEDS TO BE 21 YEARS FOR CWD TSE PRION !

                    FRIDAY, APRIL 30, 2021

                    Should Property Evaluations Contain Scrapie, CWD, TSE PRION Environmental Contamination of the land?

                    ***> Confidential!!!!

                    ***> As early as 1992-3 there had been long studies conducted on small pastures containing scrapie infected sheep at the sheep research station associated with the Neuropathogenesis Unit in Edinburgh, Scotland. Whether these are documented...I don't know. But personal recounts both heard and recorded in a daily journal indicate that leaving the pastures free and replacing the topsoil completely at least 2 feet of thickness each year for SEVEN years....and then when very clean (proven scrapie free) sheep were placed on these small pastures.... the new sheep also broke out with scrapie and passed it to offspring. I am not sure that TSE contaminated ground could ever be free of the agent!! A very frightening revelation!!!

                    ---end personal email---end...tss



                    and so it seems...

                    Scrapie Agent (Strain 263K) Can Transmit Disease via the Oral Route after Persistence in Soil over Years

                    Published: May 9, 2007

                    snip...

                    Our results showed that 263K scrapie agent can persist in soil at least over 29 months. Strikingly, not only the contaminated soil itself retained high levels of infectivity, as evidenced by oral administration to Syrian hamsters, but also feeding of aqueous soil extracts was able to induce disease in the reporter animals. We could also demonstrate that PrPSc in soil, extracted after 21 months, provides a catalytically active seed in the protein misfolding cyclic amplification (PMCA) reaction. PMCA opens therefore a perspective for considerably improving the detectability of prions in soil samples from the field.

                    snip...

                    The persistence of infectious biomolecules in soil constitutes a substantial challenge. This holds particularly true with respect to prions, the causative agents of transmissible spongiform encephalopathies (TSEs) such as scrapie, bovine spongiform encephalopathy (BSE), or chronic wasting disease (CWD). Various studies have indicated that prions are able to persist in soil for years without losing their pathogenic activity. Dissemination of prions into the environment can occur from several sources, e.g., infectious placenta or amniotic fluid of sheep. Furthermore, environmental contamination by saliva, excrements or non-sterilized agricultural organic fertilizer is conceivable. Natural transmission of scrapie in the field seems to occur via the alimentary tract in the majority of cases, and scrapie-free sheep flocks can become infected on pastures where outbreaks of scrapie had been observed before. These findings point to a sustained contagion in the environment, and notably the soil. By using outdoor lysimeters, we simulated a contamination of standard soil with hamster-adapted 263K scrapie prions, and analyzed the presence and biological activity of the soil-associated PrPSc and infectivity by Western blotting and hamster bioassay, respectively. Our results showed that 263K scrapie agent can persist in soil at least over 29 months. Strikingly, not only the contaminated soil itself retained high levels of infectivity, as evidenced by oral administration to Syrian hamsters, but also feeding of aqueous soil extracts was able to induce disease in the reporter animals. We could also demonstrate that PrPSc in soil, extracted after 21 months, provides a catalytically active seed in the protein misfolding cyclic amplification (PMCA) reaction. PMCA opens therefore a perspective for considerably improving the detectability of prions in soil samples from the field.


                    ***> This is very likely to have parallels with control efforts for CWD in cervids. <***

                    Paper

                    Rapid recontamination of a farm building occurs after attempted prion removal

                    Kevin Christopher Gough BSc (Hons), PhD Claire Alison Baker BSc (Hons) Steve Hawkins MIBiol Hugh Simmons BVSc, MRCVS, MBA, MA Timm Konold DrMedVet, PhD, MRCVS … See all authors

                    First published: 19 January 2019 https://doi.org/10.1136/vr.105054

                    Abstract

                    The transmissible spongiform encephalopathy scrapie of sheep/goats and chronic wasting disease of cervids are associated with environmental reservoirs of infectivity. Preventing environmental prions acting as a source of infectivity to healthy animals is of major concern to farms that have had outbreaks of scrapie and also to the health management of wild and farmed cervids. Here, an efficient scrapie decontamination protocol was applied to a farm with high levels of environmental contamination with the scrapie agent. Post‐decontamination, no prion material was detected within samples taken from the farm buildings as determined using a sensitive in vitro replication assay (sPMCA). A bioassay consisting of 25 newborn lambs of highly susceptible prion protein genotype VRQ/VRQ introduced into this decontaminated barn was carried out in addition to sampling and analysis of dust samples that were collected during the bioassay. Twenty‐four of the animals examined by immunohistochemical analysis of lymphatic tissues were scrapie‐positive during the bioassay, samples of dust collected within the barn were positive by month 3. The data illustrates the difficulty in decontaminating farm buildings from scrapie, and demonstrates the likely contribution of farm dust to the recontamination of these environments to levels that are capable of causing disease.

                    snip...

                    This study clearly demonstrates the difficulty in removing scrapie infectivity from the farm environment. Practical and effective prion decontamination methods are still urgently required for decontamination of scrapie infectivity from farms that have had cases of scrapie and this is particularly relevant for scrapiepositive goatherds, which currently have limited genetic resistance to scrapie within commercial breeds.24 This is very likely to have parallels with control efforts for CWD in cervids.



                    ***>This is very likely to have parallels with control efforts for CWD in cervids.

                    The transmissible spongiform encephalopathy scrapie of sheep/goats and chronic wasting disease of cervids are associated with environmental reservoirs of infectivity. Preventing environmental prions acting as a source of infectivity to healthy animals is of major concern to farms that have had outbr …



                    ***> Infectious agent of sheep scrapie may persist in the environment for at least 16 years

                    ***> Nine of these recurrences occurred 14–21 years after culling, apparently as the result of environmental contamination, but outside entry could not always be absolutely excluded.

                    JOURNAL OF GENERAL VIROLOGY Volume 87, Issue 12

                    Infectious agent of sheep scrapie may persist in the environment for at least 16 years Free

                    Gudmundur Georgsson1, Sigurdur Sigurdarson2, Paul Brown3

                    In 1978, a rigorous programme was implemented to stop the spread of, and subsequently eradicate, sheep scrapie in Iceland. Affected flocks were culled, premises were disinfected and, after 2–3 years, restocked with lambs from scrapie-free areas. Between 1978 and 2004, scrapie recurred on 33 farms. Nine of these recurrences occurred 14–21 years after culling, apparently as the result of environmental contamination, but outside entry could not always be absolutely excluded. Of special interest was one farm with a small, completely self-contained flock where scrapie recurred 18 years after culling, 2 years after some lambs had been housed in an old sheep-house that had never been disinfected. Epidemiological investigation established with near certitude that the disease had not been introduced from the outside and it is concluded that the agent may have persisted in the old sheep-house for at least 16 years.



                    Front. Vet. Sci., 14 September 2015 | https://doi.org/10.3389/fvets.2015.00032

                    Objects in contact with classical scrapie sheep act as a reservoir for scrapie transmission

                    imageTimm Konold1*, imageStephen A. C. Hawkins2, imageLisa C. Thurston3, imageBen C. Maddison4, imageKevin C. Gough5, imageAnthony Duarte1 and imageHugh A. Simmons1

                    1Animal Sciences Unit, Animal and Plant Health Agency Weybridge, Addlestone, UK

                    2Pathology Department, Animal and Plant Health Agency Weybridge, Addlestone, UK

                    3Surveillance and Laboratory Services, Animal and Plant Health Agency Penrith, Penrith, UK

                    4ADAS UK, School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, UK

                    5School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, UK

                    Classical scrapie is an environmentally transmissible prion disease of sheep and goats. Prions can persist and remain potentially infectious in the environment for many years and thus pose a risk of infecting animals after re-stocking. In vitro studies using serial protein misfolding cyclic amplification (sPMCA) have suggested that objects on a scrapie-affected sheep farm could contribute to disease transmission. This in vivo study aimed to determine the role of field furniture (water troughs, feeding troughs, fencing, and other objects that sheep may rub against) used by a scrapie-infected sheep flock as a vector for disease transmission to scrapie-free lambs with the prion protein genotype VRQ/VRQ, which is associated with high susceptibility to classical scrapie. When the field furniture was placed in clean accommodation, sheep became infected when exposed to either a water trough (four out of five) or to objects used for rubbing (four out of seven). This field furniture had been used by the scrapie-infected flock 8 weeks earlier and had previously been shown to harbor scrapie prions by sPMCA. Sheep also became infected (20 out of 23) through exposure to contaminated field furniture placed within pasture not used by scrapie-infected sheep for 40 months, even though swabs from this furniture tested negative by PMCA. This infection rate decreased (1 out of 12) on the same paddock after replacement with clean field furniture. Twelve grazing sheep exposed to field furniture not in contact with scrapie-infected sheep for 18 months remained scrapie free. The findings of this study highlight the role of field furniture used by scrapie-infected sheep to act as a reservoir for disease re-introduction although infectivity declines considerably if the field furniture has not been in contact with scrapie-infected sheep for several months. PMCA may not be as sensitive as VRQ/VRQ sheep to test for environmental contamination.

                    snip...

                    Discussion

                    SNIP...

                    In conclusion, the results in the current study indicate that removal of furniture that had been in contact with scrapie-infected animals should be recommended, particularly since cleaning and decontamination may not effectively remove scrapie infectivity (31), even though infectivity declines considerably if the pasture and the field furniture have not been in contact with scrapie-infected sheep for several months. As sPMCA failed to detect PrPSc in furniture that was subjected to weathering, even though exposure led to infection in sheep, this method may not always be reliable in predicting the risk of scrapie infection through environmental contamination.

                    These results suggest that the VRQ/VRQ sheep model may be more sensitive than sPMCA for the detection of environmentally associated scrapie, and suggest that extremely low levels of scrapie contamination are able to cause infection in susceptible sheep genotypes.

                    Keywords: classical scrapie, prion, transmissible spongiform encephalopathy, sheep, field furniture, reservoir, serial protein misfolding cyclic amplification

                    Classical scrapie is an environmentally transmissible prion disease of sheep and goats. Prions can persist and remain potentially infectious in the environme...


                    ***> 172. Establishment of PrPCWD extraction and detection methods in the farm soil

                    Kyung Je Park, Hoo Chang Park, In Soon Roh, Hyo Jin Kim, Hae-Eun Kang and Hyun Joo Sohn

                    Foreign Animal Disease Division, Animal and Plant Quarantine Agency, Gimcheon, Gyeongsangbuk-do, Korea

                    Conclusions: Our studies showed that PrPCWD persist in 0.001% CWD contaminated soil for at least 4 year and natural CWD-affected farm soil. When cervid reintroduced into CWD outbreak farm, the strict decontamination procedures of the infectious agent should be performed in the environment of CWD-affected cervid habitat.



                    KOREA CWD UPDATE 2022

                    FRIDAY, MARCH 18, 2022

                    Korea Chronic Wasting Disease CWD TSE PrP Update Increase of Positive Cases and Polymorphisms of the prion-related protein gene

                    IN 235 elks, 22 elks (9.4%) were infected with CWD.

                    IN 257 red deer, 78 red deer (30.4%) were infected with CWD.

                    IN 150 sika deer, 16 sika deer (10.7%) were infected with CWD.



                    kind regards, terry

                    Comment


                      Flounder. What is your involvement in all this? Do you work for the state? Private ranch? Biologist?

                      Comment


                        Flounder, I couldn't find the answer in the articles. Maybe I missed it. If they depopulate, how long before they can repopulate?

                        Comment


                          Originally posted by trophy8 View Post
                          Flounder. What is your involvement in all this? Do you work for the state? Private ranch? Biologist?
                          i lost my mother to the Heidenhain Variant of Creutzfeldt Jakob Disease hvCJD, confirmed, way back when Oprah was getting sued for that mad cow hamburger. watched her jerk so bad it took three grown *** adults to hold her down to keep from hurting herself. she did everything in that movie the exorcist move linda blair did except spin her her head 360 degrees, just been trying to bring awareness, just made a promise to mom, never forget, and never let them forget, show me the transmission studies...i still eat meat, pro gun, pro hunt, just don't want to eat tse prions, and you and your family shouldn't either, but that's your call. my greatest fear from this has always been friendly fire, i.e. iatrogenic transmission, from someone that has not or maybe never will go clinical, yet transmits to others via medical, dental, blood, tissue, or products there from. cwd now transmits to pigs by oral routes, lot of pig products in pharmaceuticals....





                          cjd on the rise?



                          good luck!...kind regards, terry

                          Comment


                            Originally posted by flounder9 View Post
                            i lost my mother to the Heidenhain Variant of Creutzfeldt Jakob Disease hvCJD, confirmed, way back when Oprah was getting sued for that mad cow hamburger. watched her jerk so bad it took three grown *** adults to hold her down to keep from hurting herself. she did everything in that movie the exorcist move linda blair did except spin her her head 360 degrees, just been trying to bring awareness, just made a promise to mom, never forget, and never let them forget, show me the transmission studies...i still eat meat, pro gun, pro hunt, just don't want to eat tse prions, and you and your family shouldn't either, but that's your call. my greatest fear from this has always been friendly fire, i.e. iatrogenic transmission, from someone that has not or maybe never will go clinical, yet transmits to others via medical, dental, blood, tissue, or products there from. cwd now transmits to pigs by oral routes, lot of pig products in pharmaceuticals....





                            cjd on the rise?



                            good luck!...kind regards, terry
                            Understandable and I’m sorry to hear about your mother.

                            Comment


                              Originally posted by Ag 89 View Post
                              Flounder, I couldn't find the answer in the articles. Maybe I missed it. If they depopulate, how long before they can repopulate?
                              repopulation should never happen on a cwd tse prion infected farm, 100% scorched earth policy, they are only kidding themselves when they do not depopulate complete herds imo.

                              it should be imo, by what science is showing, at least 16 years, but i would go with the 21 years from what the study showed, i posted it below.


                              This study clearly demonstrates the difficulty in removing scrapie infectivity from the farm environment. Practical and effective prion decontamination methods are still urgently required for decontamination of scrapie infectivity from farms that have had cases of scrapie and this is particularly relevant for scrapiepositive goatherds, which currently have limited genetic resistance to scrapie within commercial breeds.24 This is very likely to have parallels with control efforts for CWD in cervids.



                              ***>This is very likely to have parallels with control efforts for CWD in cervids.

                              The transmissible spongiform encephalopathy scrapie of sheep/goats and chronic wasting disease of cervids are associated with environmental reservoirs of infectivity. Preventing environmental prions acting as a source of infectivity to healthy animals is of major concern to farms that have had outbr …



                              ***> Infectious agent of sheep scrapie may persist in the environment for at least 16 years

                              ***> Nine of these recurrences occurred 14–21 years after culling, apparently as the result of environmental contamination, but outside entry could not always be absolutely excluded.

                              JOURNAL OF GENERAL VIROLOGY Volume 87, Issue 12

                              Infectious agent of sheep scrapie may persist in the environment for at least 16 years Free

                              Gudmundur Georgsson1, Sigurdur Sigurdarson2, Paul Brown3

                              In 1978, a rigorous programme was implemented to stop the spread of, and subsequently eradicate, sheep scrapie in Iceland. Affected flocks were culled, premises were disinfected and, after 2–3 years, restocked with lambs from scrapie-free areas. Between 1978 and 2004, scrapie recurred on 33 farms. Nine of these recurrences occurred 14–21 years after culling, apparently as the result of environmental contamination, but outside entry could not always be absolutely excluded. Of special interest was one farm with a small, completely self-contained flock where scrapie recurred 18 years after culling, 2 years after some lambs had been housed in an old sheep-house that had never been disinfected. Epidemiological investigation established with near certitude that the disease had not been introduced from the outside and it is concluded that the agent may have persisted in the old sheep-house for at least 16 years.


                              and for my private conversations ;

                              Should Property Evaluations Contain Scrapie, CWD, TSE PRION Environmental Contamination of the land?

                              ***> Confidential!!!!

                              ***> As early as 1992-3 there had been long studies conducted on small pastures containing scrapie infected sheep at the sheep research station associated with the Neuropathogenesis Unit in Edinburgh, Scotland. Whether these are documented...I don't know. But personal recounts both heard and recorded in a daily journal indicate that leaving the pastures free and replacing the topsoil completely at least 2 feet of thickness each year for SEVEN years....and then when very clean (proven scrapie free) sheep were placed on these small pastures.... the new sheep also broke out with scrapie and passed it to offspring. I am not sure that TSE contaminated ground could ever be free of the agent!! A very frightening revelation!!!

                              ---end personal email---end...tss



                              you can see here which farmed herd is depopulated or quarantined, and remember, a quarantined cwd infected herd is just a powder keg ready to go off, and will.



                              i remember a herd in Iowa farmed cwd infected herd, lot of court proceedings, lot of delay, only a few infected, yet while they played in the halls of justice, the cwd tse prion just kept spreading and spreading, there was a call to come cut the fences by local deer farmers, let the herd go before depopulation came. yet in the end, once depopulation occurred, there was a ***79.8 percent of the deer tested positive for the disease. i don't make this stuff up...



                              kind regards, terry
                              Last edited by flounder9; 04-21-2022, 03:19 PM.

                              Comment


                                Originally posted by diamond10x View Post
                                The flip side of the coin with that map, one could say:

                                the free range herds where breeding facilities are getting their deer from have naturally occurring CWD, therefore getting positives in their facilities.
                                Sure, problem is as soon as ONE breeder gets infected that way then they ship those deer all over the planet and we then end up with maps with dots everywhere being posted on forums.

                                Originally posted by Sippy View Post
                                What about the thousands of facilities not on the map with no cwd around. Your analysis is what I call a “convenient data extrapolation.”
                                Good thing they didn't buy a deer from an infected breeder. Those places are probably doing it right and keeping their herd healthy, kudos to them.

                                Originally posted by trophy8 View Post
                                See the post below yours. CWD didn’t just show up in a breeder pen. Nor did those deer just appear in a pen. God created it. It is naturally occurring. I just want the breeder haters to use common sense instead of reacting based on emotion and self interest(not aimed at any one person)

                                And breeder operations are tested at a far high percentage compared to free range. Kinda like Covid. Run more tests. Find more positives.
                                I'd be perfectly content with CWD naturally occurring in NM or West Texas or wherever God put it (probably came from domestic sheep scrapies though eh so can we really blame God?) but now because of shipping deer all over the country I gotta test my deer to be sure I'm not eating an infected one.

                                Comment

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